Description

The mouse monoclonal IgM Anti-A, Anti-B and Anti-AB antibodies are produced in-vitro as culture supernatant of selected hybridoma, obtained by the fusion of mouse antibody producing B-lymphocytes with mouse myeloma cells. Monoclonal sera ANTI-A, ANTI-B and ANTI-AB are specific IgM immunoglobulin which are directed against the human red blood cell antigens A, B and AB respectively. Monoclonal sera immunoglobulins are produced from individual cell line hence they are identical in their chemical structure and biological activity. The Rho (D) antigen is found on erythrocytes of approximately *5% of the Indian population. The terms Rh positive or Rh negative are understood to refer solely to the presence or absence of this antigen accordingly. Anti D (Rho) monoclonal IgM is used for the detection of the presence of Rho antigen on the red blood cells.