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Place of Origin:
CHINA
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Minimum Order Quantity:
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AS YOUR REQUIRED
Delivery Time:
1-7DAYS
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T/T
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Los Angeles, California
| CAS No.: | **********6 |
| Formula: | C*7H*5BrClFN4O3 |
| M.Wt: | **7.*8 |
| Purity: | ＞*9％ |
| Storage: | RT |
| Appearance: | Solid |
| Stock: |
Activating mutations in the BRAF gene, primarily at V**0E, are associated with poorer outcomes in patients with papillary thyroid cancer. MAPK kinase (MEK), immediately downstream of BRAF, is a promising target for ras-raf-MEK-ERK pathway inhibition. In addition to thyroid cancer, BRAF-activating mutations are prｅvalent in melanoma (**9%), colorectal cancer (5–*2%), serous ovarian cancer (**0%), and several other tumor types.
