Description

Introduction: Heparin Sodium is the sodium salt of sulfated glycosaminoglycans and is present as a mixture of heterogeneous molecules varying in molecular weights that retain a combination of activities against different factors of the blood clotting spectrum. Heparin Sodium is composed of polymers of alternating derivatives ofα-D-glucosamido (N-sulfated, O-sulfated, or N-acetylated) and O-sulfated uronic acid (α-L-iduronic acid or β-D-glucuronic acid). All sourcing of heparin material is specified and is in compliance with all applicable regulatory requirements.

Efficacy: These components have the property of prolonging the clotting time of blood. This occurs mainly through the formation of a complex of each component with the plasma proteins antithrombin and heparin cofactor II to potentiate the inactivation of thrombin (factor IIa).