Description

� � � The�*4C-Urea�Breath�Test�is�for�the�purpose�of�the�diagnosis�of�Helicobacter�pylori�infection.�A�test�kit�consists�of�a�[*4C]-Urea�capsule�and�a�collection�card.

� ��The�[*4C]-Urea�Breath�Test�(UBT)�is�based�on�the�detection�of�the�enzyme�urease,�produced�by�Helicobacter�pylori.�Since�urease�is�not�present�in�normal�human�tissues,�and�since�other�urease-producing�bacteria�do�not�colonize�the�stomach,�the�presence�of�urease�in�the�stomach�can�be�equated�with�Helicobacter�pylori�infection.
� � � �
� � �In�the�presence�of�urease,�orally�administered�*4C�urea�will�be�hydrolyzed�into�ammonia�and�*4CO2.*4CO2�is�absorbed�into�the�blood�circulation�and�exhaled�by�the�lung.�The�presence�of�a�significant�amount�of�*4CO2�in�the�exhaled�breath�indicates�active�Helicobacter�pylori�infection.

[*4C]-Urea�Breath�Test�offers�a�range�of�advantages�as�below:
Accurate
Sensitivity�*5%,�specificity�*5%***0%.
Comfortable
Non-invasive,�no�endoscopic�tube�insertion,�well�tolerated�by�patients.
Convenient
Near-patient�testing,�analysis�made�on�site,�minimal�inconvenience�for�patients.
Safe
Negligible�radiation�exposure,�has�been�exempted�from�regulation�of�radioactive�materials�in�USA�and�China.
Simple
Easy�operation,�no�special�handling�required.
Swift
The�entire�test�is�finished�in�*0�minutes,�test�result�available�on�site.

Procedure:
Take�one�*4C-�urea�capsule�with�about�*0ml�cool�drinking�water.�After�*5�minutes.�The�test-receiver�exhales�over�3�minutes�and�collects�CO2�with�sample�pipe.�
Add�diluted�scintillation�solution�4.5�ml�toward�pipe.�
Measure�sample�pipe�about�2�minutes�with�Heliscintillator�HUBT**1�
Print�results.�If�*4C-UBT?**0,�it�means�that�H.�Pylori�is�present�in�the�stomach.�If�*4C-UBT
When�the�H.�Pylori�is�effectively�treated�(eradicated)�by�antibiotics,�the�test�changes�from�positive�to�negative

Specifications:
*0�grains�(*7.8kBq�(0.*5?Ci)/grain)�of�*4C-urea�capsule/box�
*0�scintillation�bottles,�contain�gather�solution�2.0ml/bottle�(equalto�Hydrogenase�Scillarenin�Naphtylamine�2mmol/bottle)�
2�bottles�(*5ml/�bottle)�of�concentrated�scintillation�solution�
*0�roots�of�plastics�pipe


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