Description
Information
Camptothecin Extract
Type:Herbal Extract
Camptothecin Extract
Variety:Camptothecin
Camptothecin Extract
Extraction Type:Solvent Extraction
Camptothecin Extract
Grade:Medicine Grade
Camptothecin Extract
Place of Origin: China (Mainland)
Camptothecin Extract
Active Ingredient: Camptothecin by HPLC
Camptothecin Extract'
Appearance: Light yellow needle crystal
Camptothecin Extract
Botanical source: Camptotheca acuminata Decne
Camptothecin Extract
Storage: stored in cool & dry place, keep away from strong
light and heat
Camptothecin Extract
Shelf Time: 2 years while properly stored
Camptothecin Extract
Package: *5kg/drum or according to customer's requests
Camptothecin Extract Description
Camptothecine is an alkaloid derived from the
Chinese tree Camptotheca acuminata Decne. Camptothecine and its
derivative are unique in their ability to inhibit DNA topoisomerase
I, by stabilizing a covalent reaction intermediate termed the
cleavable complex which ultimately causes tumor cell death. In
clinical it is widely believed that camptontheic analogs exhibited
remarkable anti-tumour and anti- leukaemia activity. Topoisomerase
is a kind of important enzyme during DNA reproduction Process, in
charge of the winding and unwinding of the chains that make up the
chromosomal DNA Superhelix structure. If the chromosome cannot be
unwound, transcription of DNA message cannot occur and the
protein cannot be synthesized, which ultimately causes cell death.
Application of camptothecin in clinic is limited due to
serious side effects and poor water-solubility. At present, some
camptothecin analogs, either semi-synthetic or synthetic drug based
on camptothecin, have been applied cancerous therapy such as
topotecan and irinotecan while other have been obtained satisfying
curative effects in clinic.
Camptothecin ExtractMedicinal
Function
1ã€Anti-tumor,
anti-virus;
2ã€Immunosuppressive;
3ã€Anti-early
pregnancy;
4ã€The process of changing the
skin epidermal keratinocytes;
Clinical application: for
cancer, psoriasis, warts treatment, acute and chronic leukemia and
Hepatosplenomegaly caused by schistosomiasis, etc.
