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Azactam injection Aztreonam (trade names Azactam injection, Cayston inhalation) is a synthetic monocyclic beta-lactam antibiotic (a monobactam), with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum. It was approved by the U.S. Food and Drug Administration (FDA) in ***6. It is resistant to some beta-lactamases, but is inactivated by extended-spectrum beta-lactamases. Identifiers CAS number:*********0 ATC code:J*1DF*1 PubChem:CID ****6 DrugBank:APRD****5 ChemSpider:******0 UNII:G2B4VE5GH8 Chemical data Formula:C*3H*7N5O8S2 Mol. mass:**5.**3 g/mol Pharmacokinetic data Bioavailability:**0% (IM) Protein binding:*6% Metabolism:hepatic (minor %) Half-life:1.7 hours Excretion:Renal Therapeutic considerations Routes:Intravenous, intramuscular, inhalation
