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【Usage】Diagnose helicobacter Pylori(H.p) infection with non-invasive method. 【Advantage】Accurate, simple and fast diagnosis, no pain, no wound, no inter-infection and economy. 【Administration】Take one *4C-Urea capsule only. 【Principle】The presence of active Helicobacter pylori (H.p) infection can be diagnosed non-invasively with the C**4 urea breath test (UBT). This test is based on the detection of the enzyme urease, produced by Helicobacter pylori. Since urease is not present in normal human tissues, and since other urease-producing bacteria do not colonize the stomach, the presence of urease in the stomach can be equated with Helicobacter pylori infection. In the presence of urease, orally administered C**4 urea will be hydrolyzed into ammonia and *4CO2. *4CO2 is absorbed into the circulation and exhaled by the lungs. The presence of a significant amount of *4CO2 in the exhaled breath indicates active Helicobacter pylori infection. 【Procedure】 　1. Take one *4C- urea capsule with about *0ml cool drinking water. After *5 minutes. The test-receiver exhales over 3 minutes and collects CO2 with sample pipe. 　2. Add diluted scintillation solution 4.5 ml toward pipe. 　3. Measure sample pipe about 2 minutes with Heliscintillator HUBT**1 4. Print results. If *4C－UBT≥**0, it means that H.pylori is present in the stomach. If *4C－UBT＜**0, H.pylori is not present. When the H.pylori is effectively treated (eradicated) by antibiotics, the test changes from positive to negative.