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Ribonuclease A
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Ribonuclease A

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Persona de contacto Mr. jack

tianhe, guangzhou, Other

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Especificaciones del producto

  • Purity (%): 99.9
  • Brand Name: GENESHUN

Descripción del producto

Cat#ES***1 **0mg

Cat#ES***2 1g



Storage Temperature: **0° C

CAS# ********4

Grade: High purity grade, for Molecular Biology

Specific activity: ≥ *0 Kunitz units/mg of protein



Product Description

A major application for Ribonuclease A (RNAse A) is the removal of RNA from preparations of plasmid DNA. In this application, the presence of DNAse activity as an impurity is a concern. The boiling-water bath method used to eliminate contaminating DNase acitivity has proven unreliable. RNAse A is an endoribonuclease that attacks at the 3'phosphate of a pyrimidine nucleotide.



The sequence of pG-pG-PC-pA-pG will be cleaved to give pG-pG-pCp and A-pG. The highest activity is exhibited with single stranded RNA. RNAse A is a single chain polypeptide containing 4 disulfide bridges. In contrast to RNAse B, it is not a glycoprotein. RNAse A can be inhibited by alkylation of His*2 or His**9, which are present in the active site of the enzyme. Activators of RNAse A include potassium and sodium salts.



This product is stable for at least 4 years when stored properly at **0° C.

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