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Ezetimibe CAS:163222-33-1
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Ezetimibe CAS:163222-33-1

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Persona de contacto Cecilia

Wuhu, Anhui

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Especificaciones del producto

  • Grade Standard: Medicine Grade

Descripción del producto


Product Name:
Ezetimibe
Synonyms: *-(*-fluorophenyl)**-[*-(*-fluorophenyl)**-hydroxy-propyl]**-(*-hydroxyphenyl)-azetidin**-one;EZETIMIBE;ZETIA;Ezitimibe∬EzetimibeC*4H*1F2N*3;(3R,4S)**-(*-Fluorophenyl)**-[(3S)**-(*-fluorophenyl)**-hydroxypropyl]**-(*-hydroxyphenyl)**-azetidinone, Sch*****5;*-(*-Flurophenyl)-(3R)**-(*-flurophenyl)-(3S)-hydroxypropyl-(4S)-(*-hydroxyphenyl)**-azetidinone;Ezetimide
CAS: **********1
MF: C*4H*1F2NO3
MW: **9.*3
EINECS:  
Mol File: **********1.mol
 

 
Purity:>*9.5% Package:**0g,**0g,1kg,*0kg


Biological Activity of Ezetimibe
Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density lipoprotein (LDL) cholesterol when added to statin treatment.
IC*0 value:
Target: cholesterol-absorption
Ezetimibe is a lipid-lowering drug that inhibits the intestinal absorption of dietary and biliary cholesterol by blocking passage across the intestinal wall. In patients with familial hypercholesterolemia, combined therapy with ezetimibe and simvastatin did not result in a significant difference in changes in intima-media thickness, as compared with simvastatin alone, despite decreases in levels of LDL cholesterol and C-reactive protein. (ClinicalTrials.gov number, NCT*******7.) Ezetimibe offers a new therapeutic option for patients receiving statins who require further reduction in LDL cholesterol.
Chemical Information

M.Wt
**9.*3 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Formula C*4H*1F2NO3
CAS No **********1
Solvent & Solubility
DMSO:*2mg/ml; ethanol:*2mg/ml;
 

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